The Spanish flu killed more Americans in one year than the combined total who died in battle during WWI, WWII, the Korean War, and the Vietnam War.
On the day the Roman Colosseum officially opened, 5,000 animals were killed. During its history, it has been estimated that over 500,000 people and over a million animals were killed there.
Corn dextrin, a common thickener used in junk food, is also the glue on envelopes and postage stamps.